Interesting topic.
Drag Radials while grippy, in my experience need serious heat to get their grip. Which usually requires a smoky RWD burnout that is not usually possible with our AWD cars. But to be fair it has been a long time since I've used drag radials and new compounds might be better.
I've never had R compound but I think it might be similar where they really get their ultimate grip from heat due to road course laps.
At "regular" temps I don't know that either offers much more grip than a max performance summer tire.
My preference is just the best summer tire I can get. PSS PS4S etc. I'm not switching tires at the track.
It makes me wonder if you could submit that question to one of these tire review youtuber guys who have the means to try out several tires and see what they find out.
https://www.youtube.com/user/TyreReviews
I saw a couple guys who seemed to really like the Toyo R888R on their Stangs. (Operating Temperature: 160°-220° F)
As for wheels my understanding for drag racing is usually smaller is better, but that may apply to overall wheel/tire diameter too...smaller diameter accelerates faster. I'm not sure if you're willing to go that route.
Honestly I thought your HRE P107 was near the pinnacle of strong/light wheels. I mean even at 21x10.5 what are they like 23 lbs?
I had 20x9 Rohana RF2's I thought were pretty light at 24 lbs but your HRE's put them to shame. (jealous)

The lightest wheels I've ever looked into were the BBS FI-R that for 20x9 weigh only 17 lbs.! However I spoke to BBS directly and they said they are not load rated for the S6/S7/RS7 just the front axle of Huracan even though one user has them installed on his S6 without any known issue. I believe BBS's exact stance was they would sell them, but would not stand by their warranty if installed on an S6. (Not sure how they would know...speculate police report. Ha)
FWIW I have no real proof but when I went from stock wheels to the lighter RF2's with PSS's I felt like I lost grip and spun more often off the line...at the strip anyway... on the street traction always felt better so I chalked it up to bad track prep but maybe it had something else to do with the lightweight wheels. I look forward to finding out more this spring as I now have heavier than RF2's (24lbs), but lighter than stock(30lbs), HRE FF01's(27lbs) but I have coupled them with a 265 instead of stock 255 so the total weight is only 1lb less than stock. But I also ran my personal best 11.66 on the stock tires/wheels.
Anyway, interested to see other's thoughts.
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