Nitrous is proven for spooling large turbos, but you will probably get better feedback on other forums as others noted (big turbo mustang, camaro, vette, supra, EVO type setups). I suspect though that you will find many running the NOS to spool the turbo will be using race fuel vs meth. NOS + meth just leads to more potential things to go wrong and not many people running it likely for that reason.
I did consider it on my old '04 Cobra before I sold the car. I had meth running on the car and installed a J&S Safeguard (knock sensor) which has capability of retarding ignition timing with Nitrous. I also had a device which would cut spark/fuel if air/fuel would get out of wack based on a wideband sensor. That car's a different animal, but the point is I was trying to play it safe... this was anticipating install of a 75-100hp wet shot, but ended up selling the car before I went that route. I had a Kenne Bell supercharger on the car and knew others with the same running meth + Nitrous and the Nitrous was making a significant power advantage. The idea behind this vs E85 or race fuel was the latter was not readily available or cost prohibitive and the E85 required significantly more fuel pump and injector and I was already running twin Ford GT pumps and fairly large injectors (anything larger required a complete fuel system revamp). A wet shot along with a Kenne Bell boost a pump (voltage amplifier for fuel pump) was enough to avoid costly fuel system upgrades and still get me the sizeable pump in power.
All in all, if you tune for both meth and Nitrous, the safer the install the better... run as many fail safes as possible to avoid engine damage (nitrous pressure gauge, meth level sensor,etc).
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